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Why are generic medicines so cheap?

Unlike generic drugs, a large part of the costs incurred by original manufacturers of brand name drugs are for research and development and advertising. The expense of obtaining FDA approval alone in the U.S. is enormous. Manufacturers of generic drugs do not have to absorb or recover these costs. Consequently, significant cost savings can be passed along to you.

Generic TopamaxAnti Convulsants / Generic Topamax
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100mg × 300 pills$622.00US $ 2.07Buy
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Topiramate is used for:

  • Treating certain kinds of seizures in patients 2 years of age or older. It is also prescribed to prevent migraine headache in adults.
  • Topiramate is a carbonic anhydrase inhibitor. It works by controlling nerve impulses in the brain.

Do NOT use Topiramate if:

    • you are allergic to any ingredient in Topiramate
    • you are taking other carbonic anhydrase inhibitors (eg, acetazolamide)
  • Contact your doctor or health care provider right away if any of these apply to you.

Before using Topiramate :

    • Some medical conditions may interact with Topiramate . Tell your health care provider if you have any medical conditions, especially if any of the following apply to you:
      • if you are pregnant, plan to become pregnant, or are breast-feeding
      • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
      • if you have allergies to medicines, foods, or other substances
      • if you have liver or kidney problems, kidney stones, or regularly consume alcohol
      • if you have diarrhea, a respiratory tract disease, or you are scheduled for surgery
      • if you have status epilepticus (continuous seizure activity or a series of seizures without a full return to consciousness)
      • if you are on a diet that increases the amount of ketones in your blood and results in fruity-smelling breath
    • Some MEDICINES MAY INTERACT with Topiramate . Tell your health care provider if you are taking any other medicines, especially any of the following:
      • Carbamazepine or hydantoins (eg, phenytoin) because the effectiveness of Topiramate may be decreased
      • Amitriptyline, carbamazepine, hydantoins (eg, phenytoin), or metformin because the actions and side effects of these medicines may be increased
      • Risperidone because its effectiveness may be decreased by Topiramate
    • This may not be a complete list of all interactions that may occur. Ask your health care provider if Topiramate may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

    How to use Topiramate :

    • Use Topiramate as directed by your doctor. Check the label on the medicine for exact dosing instructions.
      • Topiramate may be taken with or without food.
      • Drink plenty of fluids while taking Topiramate to prevent kidney stones from forming.
      • Swallow Topiramate whole. Do not crush, break, or chew before swallowing.
      • Suddenly stopping Topiramate may cause seizures to occur more often. Stopping therapy should be gradual.
      • If you miss a dose of Topiramate , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.
    • Ask your health care provider any questions you may have about how to use Topiramate .

    Important safety information:

    • Topiramate may cause dizziness, drowsiness, confusion, difficulty concentrating, or blurred vision. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Topiramate . Using Topiramate alone, with other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.
    • Avoid drinking alcohol or taking other medications that cause drowsiness (eg, sedatives, tranquilizers) while taking Topiramate . Topiramate will add to the effects of alcohol and other depressants. Ask your pharmacist if you have questions about which medicines are depressants.
    • Topiramate may reduce sweating, which could raise body temperature, especially in children. The risk of this serious side effect is greater in hot weather and/or during vigorous exercise. Drink plenty of fluids and dress lightly while in hot climates or when exercising. Check carefully for signs of decreased sweating. If this occurs, promptly seek cooler or air-conditioned shelter and/or stop exercising. Seek immediate medical attention if your body temperature is above normal, or if you have mental or mood changes, headache, or dizziness.
    • Additional monitoring of your dose or condition may be needed if you are taking other medicines that reduce sweating. These medicines include anticholinergics (eg, benztropine), amitriptyline, haloperidol, or carbonic anhydrase inhibitors (eg, acetazolamide).
    • Topiramate may result in a change in the acidity (pH) of your blood. If you experience loss of appetite, changes in breathing, tiredness, or change in heart rhythm, contact your health care provider.
    • Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are taking Topiramate .
    • Topiramate may decrease the effectiveness of your birth control pill. To prevent pregnancy, be sure to use an additional form of birth control while using Topiramate .
    • Diabetic patients - Topiramate may alter blood sugar levels in patients taking metformin. Check your blood sugars more frequently and contact your doctor for dose changes.
    • LAB TESTS, such as serum bicarbonate, may be performed to monitor your progress. Be sure to keep all doctor and lab appointments.
    • Topiramate is not recommended for use in CHILDREN under the age of 2 years; safety and effectiveness in this age group have not been confirmed.
    • . PREGNANCY and BREAST-FEEDING: If you plan on becoming pregnant, discuss with your doctor the benefits and risks of using Topiramate during pregnancy. Topiramate is excreted in breast milk. If you are or will be breast-feeding, check with your doctor to discuss the risks to your baby.

    Possible side effects of Topiramate :

    • All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
      • Abnormal skin sensations (numbness or tingling, decreased sensitivity)
      • abnormal walking
      • agitation or aggression
      • appetite loss
      • back pain
      • breast pain
      • change in speech
      • clumsiness
      • coordination decreased
      • confusion
      • constipation
      • decreased hearing
      • decreased sweating
      • depression
      • diarrhea
      • difficulty with concentration or attention
      • dizziness
      • drowsiness
      • dry mouth
      • fatigue
      • flu-like symptoms
      • hot flushes
      • injury
      • indigestion
      • infection
      • itching
      • leg pain;menstrual disorder;mood swings
      • muscle pain or contractions
      • nausea
      • nervousness or anxiety
      • runny nose
      • saliva increased
      • sex drive decreased
      • sinus swelling
      • skin disorder
      • stomach pain or ache
      • strange taste
      • sore throat
      • thinking problems
      • thirst
      • tremor
      • unstable emotions
      • vomiting
      • weakness.
    • Seek medical attention right away if any of these SEVERE side effects occur:
      • Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue)
      • blood in the urine
      • blurred vision or sudden worsening of vision
      • chest pain
      • difficulty concentrating
      • fast, deep breathing
      • feeling of moving slowly
      • increased body temperature
      • irregular heartbeat
      • loss of consciousness
      • memory problems
      • painful/red eyes;prostate problems;severe stomach pain
      • significant weight loss
      • speech problems
      • stupor
      • unexplained fever
      • unusual eye movements
      • unusual tiredness
      • urinary incontinence
      • urinary tract infection.

    What is the shelf life of the pills?

    • The expiry date is mentioned on each blister. It is different for different batches. The shelf life is 2 years from the date of manufacture and would differ from batch to batch depending on when they were manufactured.



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06.09Low glycogen level could explain violent drunks: study
HELSINKI (AFP) – Low glycogen levels could explain why some people always turn aggressive or violent when they drink, a Finnish study showed Monday, suggesting the problem could be avoided with medication and regular meals.
05.09Study Reported Tadalafil Taken Once Daily Improved Erectile Function In Men With ED And Sexual Quality Of Life In Couples.
Eli Lilly and Company (NYSE: LLY) announced results from a double-blind, placebo-controlled study which showed that tadalafil 5 mg dose taken once daily was generally well-tolerated, improved erectile function for men with erectile dysfunction (ED) and reported improvement in the sexual quality of life scores for men and their female partners. The 12-week study monitored 342 men and their partners, using several scientific questionnaires to assess changes in erectile function and sexual quality of life before and after treatment with a tadalafil once daily dose. The study appears in the May issue of the peer-reviewed Journal of Sexual Medicine.

"This is the first study of tadalafil 5 mg once daily dose in the treatment of men with ED in which the female partner reported improvement in sexual quality of life scores," said lead investigator Eusebio Rubio-Aurioles M.D., Ph.D. "The sexual quality of life scores also improved among males being treated. In addition, this study showed that daily dose of tadalafil is effective and generally well tolerated in the treatment of erectile dysfunction."

04.09Erectile Dysfunction: Cialis, Viagra and Levitra to Treat ED.
There are only three oral drugs approved by the FDA to treat erectile dysfunction: Cialis, Levitra, and Viagra. All work by increasing the flow of blood into the penis so that when a man is sexually stimulated, he can get an erection.

What Are the Differences Between Cialis, Levitra, and Viagra?

Cialis, Levitra, and Viagra work by a similar mechanism to cause erections. There are subtle differences in how long the drug works and how quickly it works. Levitra works a little longer than Viagra. They both take effect in about 30 minutes. With Levitra, the effects last for about 5 hours. With Viagra, the effects last approximately 4 hours.

Cialis works a bit faster (within about 15 minutes), and the effects last much longer -- up to 36 hours in some cases.

If One of These Drugs Isn't Effective for Erectile Dysfunction, Can I Try Another?

Yes, but because these drugs work the same way, it's unlikely that you'll have success with one if you've failed to achieve an adequate erection with another.

What Precautions Should I Take Before Taking One of These Drugs?

There are certain situations in which these drugs may not be safe to take. Before taking them, tell your doctor:

* If you are allergic to any drugs, including Viagra or other ED medications.

* About any prescription or nonprescription medications you are currently taking, including herbal and dietary supplements.

* If you are scheduled for surgery, including dental surgery.

* If you take nitroglycerin or a long-acting nitrate to treat chest pain. The combination of Cialis, Levitra or Viagra with these drugs can cause dangerously low blood pressure.

* If you take alpha-blockers for blood pressure or prostate problems. The combination of Cialis or Levitra with these drugs can also cause dangerously low blood pressure.


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